The challenge against champions Chlesea on Sunday is for Manchester United to show that they can replicate the confident and businesslike win that City showed a month ago.
Germany midfielder Toni Kroos has eased Real Madrid's injury concerns and could be fit to play in their Champions League match at Borussia Dortmund on Tuesday, coach Zinedine Zidane said.
Liverpool's Egyptian forward Mohamed Salah scored his 29th Premier League goal six minutes from time to secure a 2-1 win at Crystal Palace that took them up to provisional second spot in the table on Saturday.
A summary of Wednesday's action in the Premier League.
Images from the English Premier League matches played on Sunday
Pogba suffered the injury in United's 3-0 Champions League win over Basel this month.
Robert Huth's double and a Riyad Mahrez goal sent Premier League leaders Leicester City six points clear after a stunning 3-1 victory at shell-shocked title rivals Manchester City on Saturday.
London clubs' erratic start to the Premier League season improved with victories for Chelsea, Tottenham Hotspur and Arsenal on Saturday but Manchester sides continued to make the running, with City and United the top two.
Summary of all that transpired on and off the football field
IMAGES from the English Premier League matches played on Sunday.
Mourinho's tinkerings meant a first start of the season for midfielder Scott McTominay, playing on the right of a three-man defence, while Anthony Martial played instead of the dropped Alexis Sanchez. On this evidence, more changes may be needed when United take on Valencia in the Champions League on Tuesday.
IMAGES from the English Premier League matches played on Sunday
Leicester's Mahrez finds form in time for January sales
Liverpool striker Daniel Sturridge was substituted with a thigh injury as the English Premier League club beat Bayern Munich 3-0 in a pre-season match in Germany on Tuesday.
News of all that's transpired on and off the football field
Four months after quitting Liverpool for Manchester City, Raheem Sterling will have the first opportunity to justify the move by getting one over his former employers when the teams meet at the Etihad Stadium on Saturday.
Manchester City came from behind twice to earn a 2-2 draw with Liverpool in a breathless and pulsating Premier League encounter, at Anfield, on Sunday. All four goals came in the second half.
Pressure is something that Liverpool manager Brendan Rodgers says comes with the territory, but after a dismal run, the odds on him becoming the season's first managerial casualty are swiftly shortening.
Manchester United manager Jose Mourinho has promised to show plenty of restraint and respect if he inflicts a first Premier League defeat of the season on his former side Chelsea on Saturday.
Summary of sports events and persons who made news on Friday.
Real Madrid forward Vinicius Jr. score twice as his side punished a sloppy Liverpool to win 3-1, while Manchester City beat Borussia Dortmund 2-1 in Tuesday's Champions League quarter-final first leg.
Real Madrid captain Sergio Ramos risks being hit with an extra game suspension which would rule him out of a potential Champions League quarter-final first leg after admitting he got booked on purpose in Wednesday's 2-1 win at Ajax Amsterdam.
How quickly affections can switch in soccer. Where once they would serenade coach Jose Mourinho at Stamford Bridge with an operatic flourish, now Chelsea fans have fallen headlong for another man driving them inexorably to the Premier League title.
City are looking to retain the title they won in record-breaking fashion last year and secure their fourth Premier League crown in eight years.
A preview of the line-up action in the English Premier League
Manchester City forward Raheem Sterling struck twice as the Premier League champions beat Crystal Palace 3-1 at Selhurst Park on Sunday to go top of the table and heap pressure on title rivals Liverpool.
In their first match since manager Claudio Ranieri was sacked after five successive defeats in which they failed to score a goal, Leicester produced the kind of vibrant display that carried them to glory last May.
'Keep Calm And Carry On' could be Claudio Ranieri's motto for the second half of the season after Leicester City earned a 1-0 win at Tottenham Hotspur on Wednesday to put the heat back on Premier League leaders Arsenal.
IMAGES from the Champions League matches played on Tuesday.
Messi, whose deal expires in 2021, had called his side "weak" and "inconsistent" after they lost the league title to Real Madrid.
Images from the English Premier League matches played across England on Tuesday
Raheem Sterling scored a second-half hat-trick as leaders Manchester City beat Watford 3-1 on Saturday while Liverpool kept the gap at one point by overcoming Burnley 4-2 on Sunday.
Liverpool romed into the Europa League final with a 3-0 win over Villarreal on another magical night at Anfield to tee up a showpiece clash with holders Sevilla who swatted away visitors Shakhtar Donetsk 3-1 on Thursday.
IMAGES from the English Premier League matches played on Wednesday.
Chelsea maintained their stranglehold on the Premier League by beating Sunderland 1-0 on Wednesday to register their 10th successive win and move six points clear at the top of the table.
News of all that's transpired on and off the football field
Reigning champions Manchester City took the lead after 24 seconds but suffered a shock 2-1 defeat at Newcastle United.
Liverpool added another fairytale comeback to the history books as they fought back from 3-1 down against Borussia Dortmund to reach the Europa League semi-finals after Dejan Lovren's towering stoppage-time header secured a 4-3 win on Thursday.
Ibrahimovic was forced off with a muscle problem with 11 minutes remaining, and the Swede was pictured sitting on the bench with an ice pack strapped to the back of his left leg.
A summary of Sunday's action in the Premier League.